Fractional CO2 laser vs Intralesional Corticosteroids in Alopecia Areata: A comparative study of Efficacy, Safety and Predictive factors
DOI:
https://doi.org/10.63666/ejsmr.1694-9013.3.I.2025.65Keywords:
Fractional CO2, alopecia areata, steroid injection, effectivenessAbstract
Objective: The aim of the present study was to compare the effectiveness of Fractional CO2 laser with Intra lesional steroid injection in treament of alopecia areata. Methodology: This Clinical trial was carried out among 60 patients attending Outpatient department of Dermatology and Venereology of Combined Military Hospital, Dhaka within the defined period from January 2024 to June 2024. Permission was taken from the Administrative Head of the Hospital authority to collect data. Purposive sampling was done according to availability of the patients. Informed written consent was taken from each Participant. Privacy and confidentiality was maintained strictly. The collected data were entered into the computer and analyzed by using SPSS (version 20.1). Patient diagnosed with alopecia areata by qualified Dermatologists will be enrolled for the study. Result: The CO2 laser group demonstrated superior outcomes, with 23 patients (76.7%) achieving clinically significant response (≥ 50% regrowth) compared to 14 patients (46.7%) in the intralesional corticosteroid injection (ILC) group (p= 0.020). This represents a 30% absolute improvement and a 3.79- fold higher odd of treatment success with fractionated CO2 laser therapy. Treatment failure was relatively higher 08 (26.7%) in ILC group, (p= 0.097) Conclusion: Fractional CO2 laser could be a better therapeutic alternative for treating alopecia areata in comparison to traditional Intralesional corticosteroid injection due to less complication.
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